Lennart Truedsson Selected Research

Hereditary Complement Deficiency Diseases

12/2018	Inherited Classical and Alternative Pathway Complement Deficiencies in Children: A Single Center Experience.
11/2015	European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager: Mohamed R. Daha.
8/2015	Heat differentiated complement factor profiling.
8/2010	Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases.
1/2009	Genetic, molecular and functional analyses of complement factor I deficiency.
12/2007	Complement deficiencies and systemic lupus erythematosus.
9/2007	Complement analysis in the 21st century.
11/2006	Properdin deficiency in a boy with fulminant meningococcal septic shock.

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Lennart Truedsson Research Topics

Disease

20	Systemic Lupus Erythematosus (Libman-Sacks Disease) 11/2022 - 01/2004
10	Infections 12/2018 - 07/2003
10	Rheumatoid Arthritis 05/2015 - 01/2005
9	Inflammation (Inflammations) 01/2019 - 08/2002
8	Hereditary Complement Deficiency Diseases 12/2018 - 11/2006
6	Autoimmune Diseases (Autoimmune Disease) 08/2012 - 02/2008
5	Arthritis (Polyarthritis) 05/2015 - 01/2006
5	Spondylarthropathies 05/2015 - 01/2006
3	Vasculitis (Vasculitides) 01/2019 - 01/2005
2	Lupus Nephritis 01/2019 - 02/2014
2	Bacterial Infections (Bacterial Infection) 12/2018 - 07/2003
2	Glomerulonephritis 12/2018 - 01/2005
2	Acute Coronary Syndrome 10/2016 - 01/2009
2	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2016 - 01/2015
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2016 - 01/2016
2	Necrosis 05/2015 - 07/2012
2	Rheumatic Diseases (Rheumatism) 01/2014 - 08/2012
2	Celiac Disease (Celiac Sprue) 01/2014 - 02/2005
2	Disease Susceptibility (Diathesis) 07/2012 - 01/2004
1	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 01/2019
1	Hereditary Angioedemas 12/2018
1	Exanthema (Rash) 12/2018
1	Multiple Organ Failure (MODS) 01/2016
1	Pneumococcal Infections 05/2015
1	Purine Nucleoside Phosphorylase Deficiency 01/2015
1	Ataxia (Dyssynergia) 01/2015
1	Proteinuria 01/2014
1	Alopecia (Baldness) 01/2014
1	Stroke (Strokes) 01/2014
1	Primary Immunodeficiency Diseases 01/2014
1	Pleurisy (Pleuritis) 01/2014
1	Lymphopenia (Lymphocytopenia) 01/2014
1	Thrombosis (Thrombus) 01/2014
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2014
1	Venous Thromboembolism 11/2013
1	Cardiovascular Diseases (Cardiovascular Disease) 11/2013
1	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 01/2013
1	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 01/2013
1	Microscopic Polyangiitis 01/2013
1	Kidney Diseases (Kidney Disease) 01/2011

Drug/Important Bio-Agent (IBA)

11	Complement System Proteins (Complement)IBA 11/2022 - 11/2006
6	AutoantibodiesIBA 01/2019 - 12/2007
6	Antigen-Antibody Complex (Immune Complex)IBA 12/2018 - 01/2004
6	Immunoglobulin G (IgG)IBA 08/2012 - 07/2003
5	Methotrexate (Mexate)FDA LinkGeneric 01/2016 - 01/2006
5	Proteins (Proteins, Gene)FDA Link 08/2015 - 09/2010
4	Fibrinogen (Factor I)FDA Link 01/2019 - 01/2007
3	AntibodiesIBA 01/2019 - 02/2005
3	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 05/2015 - 07/2012
3	Analgesics (Analgesic Drugs)IBA 05/2015 - 07/2012
3	Conjugate VaccinesIBA 05/2015 - 01/2013
3	Immunoglobulin A (IgA)IBA 01/2014 - 07/2003
3	Polysaccharides (Glycans)IBA 08/2012 - 07/2006
3	Immunoglobulins (Immunoglobulin)IBA 07/2012 - 07/2003
3	CytokinesIBA 04/2011 - 03/2004
3	Interferon Type IIBA 04/2011 - 09/2008
2	VaccinesIBA 12/2018 - 12/2011
2	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 12/2018 - 12/2011
2	ProperdinIBA 12/2018 - 11/2006
2	Complement Factor H (Factor H)IBA 08/2015 - 01/2011
2	AntigensIBA 02/2014 - 02/2005
2	Antirheumatic Agents (DMARD)IBA 01/2013 - 07/2012
2	Heptavalent Pneumococcal Conjugate Vaccine (Prevnar)IBA 07/2012 - 12/2011
2	Complement Inactivating AgentsIBA 01/2011 - 01/2009
2	Mannose-Binding Lectin (Mannan-Binding Lectin)IBA 01/2009 - 07/2006
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 04/2007 - 01/2004
2	HLA-DRB1 Chains (HLA DRB1)IBA 09/2006 - 01/2005
2	MannansIBA 07/2006 - 01/2005
2	Complement Factor B (Factor B)IBA 07/2006 - 07/2003
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2019
1	Lupus Coagulation Inhibitor (Lupus Anticoagulant)IBA 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 12/2018
1	P-SelectinIBA 10/2016
1	Prasugrel Hydrochloride FDA Link 10/2016
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2016
1	Cortisone FDA Link 01/2016
1	thymoglobulin FDA Link 01/2016
1	Prednisolone (Predate)FDA LinkGeneric 05/2015
1	Laminin (Merosin)IBA 02/2014
1	LigandsIBA 02/2014
1	Nucleosomes (Nucleosome)IBA 02/2014
1	anti-dsDNA autoantibodyIBA 01/2014
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2014
1	S100A12 ProteinIBA 11/2013
1	Biological ProductsIBA 10/2013
1	tocilizumab (atlizumab)FDA Link 10/2013
1	Rituximab (Mabthera)FDA Link 10/2013
1	Abatacept (Orencia)FDA Link 10/2013
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/2013
1	Complement C3 (C3 Complement)IBA 01/2013
1	Myeloblastin (Proteinase 3)IBA 01/2013
1	Peroxidase (Myeloperoxidase)IBA 01/2013
1	Histones (Histone)IBA 08/2012
1	Glycoside Hydrolases (Endoglycosidases)IBA 08/2012
1	Tumor Necrosis Factor InhibitorsIBA 12/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2011

Therapy/Procedure

2	Hematopoietic Stem Cell Transplantation 01/2016 - 01/2015
1	Transplantation 01/2016
1	Therapeutics 08/2011